Gamma Knife Radiosurgery For Patients With Imaging-diagnosed Orbital Cavernous Hemangioma.Xiaomin Liu, MD, PhD11Department of Neurosurgery and Gamma Knife Center, 2ND Hospital of Tianjin Medical University Keywords: brain tumor, orbit, cavernous hemangioma, gamma knife, outcomeInteractive Manuscript
Ask Questions of this Manuscript:
What is the background behind your study?
What is the purpose of your study?
To evaluate clinical outcome and tumor control of imaging-diagnosed orbital cavernous hemangiomas (OCHs) treated with gamma knife radiosurgery (GKS).
Describe your patient group.
Between 1995 and 2008, a total of 23 imaging-diagnosed OCHs were treated with GKS and complete follow-up was available.
Describe what you did.
The mean treatment volume was 2.02 cm3 (range 0.15-10.10); the mean tumor margin dose was 15.3 Gy (range 12-20) and the mean follow-up was 23.5 months (range 6-120).
Describe your main findings.
Decrease in tumor size was found in 20 cases and no tumor progression was observed after GKS. Eleven of 14 patients with affected visual function prior to treatment showed improvement in visual acuity at the last assessment. Side-effects included orbital pain in 3 patients and chemosis in 2 patients.
Describe the main limitation of this study.
This is a retrospective study.
Describe your main conclusion.
In this preliminary experience GKS proved to be an effective treatment modality for imaging-diagnosed OCHs.
Describe the importance of your findings and how they can be used by others.
Additional follow-up is necessary and long term side-effects are yet to be determined.
To evaluate clinical outcome and tumor control of imaging-diagnosed orbital cavernous hemangiomas (OCHs) treated with gamma knife radiosurgery (GKS).
Between 1995 and 2008, a total of 23 imaging-diagnosed OCHs were treated with GKS and complete follow-up was available.
The mean treatment volume was 2.02 cm3 (range 0.15-10.10); the mean tumor margin dose was 15.3 Gy (range 12-20) and the mean follow-up was 23.5 months (range 6-120).
Decrease in tumor size was found in 20 cases and no tumor progression was observed after GKS. Eleven of 14 patients with affected visual function prior to treatment showed improvement in visual acuity at the last assessment. Side-effects included orbital pain in 3 patients and chemosis in 2 patients.
This is a retrospective study.
In this preliminary experience GKS proved to be an effective treatment modality for imaging-diagnosed OCHs.
Additional follow-up is necessary and long term side-effects are yet to be determined.
Project Roles:
X. Liu ()
